In a statement on X, Vice President JD Vance said ICE is now 'going to work even harder.'

'I want every ICE officer to know that their president, vice president, and the entire administration stands behind them,' he said.

'To the radicals assaulting them, doxxing them, and threatening them: congratulations, we're going to work even harder to enforce the law.'

Noem said at the news conference that Renee Nicole Good had been 'stalking' immigration enforcement agents prior to the shooting.

'It’s very clear that this individual was harassing and impeding law enforcement operations,' she said, before calling on federal prosecutors to charge individuals who use their vehicles to ram ICE agents as domestic terrorism.

The Department of Homeland Security said they were acting in self-defense when the agent opened fire.

The former brother-in-law of a mother shot dead by an ICE agent during immigration operations in Minneapolis has argued she 'should have minded her own business.'

Good's former brother-in-law Joseph Macklin has weighed in on the tragedy, telling the Daily Mail on Wednesday night she put herself in a dangerous situation without reason.

Minneapolis Mayor Jacob Frey was asked on CNN about his remarks calling on ICE to 'get the f**k out of' the city.

'I'm so sorry if I offended your Disney princess ears,' he replied.

'But here's the thing: If we're talking about what's inflammatory, on one hand you got someone who dropped an F-bomb and on the other hand you have someone who killed somebody else, I think the more inflammatory action is killing somebody.'

'And so once again, let's be real and honest and straight up about what's happening here, this is not OK - the way they're coming into cities, not just Minneapolis, but around the country is not OK.'

'You want to make a big deal about an F-bomb,' Frey later added, 'I think let's make a big deal about our Constitution, I think that's probably the better route.'

Border Czar Tom Homan decried 'reckless' rhetoric in the aftermath of the shooting.

'I think it's reckless what I'm seeing on social media,' he told CBS Evening News' Tony Dokoupil. 'I've seen seven or eight members of Congress make the comment that ICE just murdered somebody.

'The investigation's ongoing,' he said.

'The comments about murder is going to incite more violence, more threats and hopefully not more bloodshed.'

Sen. Chris Van Hollen, of Maryland, declared that the American public 'cannot trust a word coming out of' the Trump administration.

He wrote on X that he has rewatched the video of the shooting.

'It is grotesque to hear Kristi Noem justify her killing as a response to "domestic terrorism” & for Trump to spread further lies on social media,' van Hollen posted.

'We need immediate answers & accountability — we cannot trust a word coming out of this Administration.'

Sen. Brian Schatz, of Hawaii, has likened the ICE-involved shooting to Japanese internment.

'A six year old is an orphan because the government shot the mom, and now they are lying about it,' he posted on X.

'This conduct will go down in infamy like the govt agents who kidnapped native kids, or those who incarcerated Japanese Americans. Shame, forever.'

Illinois Governor JB Pritzker called on US Homeland Security Secretary Kristi Noem to resign from office.

'For months, Trump’s DHS has wreaked lawless havoc in our neighborhoods. Tear gassing infants, families, and police. Firing their weapons at peaceful citizens. Killing innocent people,' he posted on social media.

'It’s brutal, unconstitutional, and out of control.

'It must stop.

'Kristi Noem must go. Now.'

Protests against Immigration and Customs Enforcement have sprang up in cities across the country, including New York, Minneapolis, Chicago and even Anchorage, Alaska.

Disturbing video from Minneapolis showed an armed ICE agent grabbing a protester in a green jacket and pushing him to the ground, before deploying pepper spray at the crowd.

The officer could then be seen pushing others out of the way as the crowd called out 'Cowards' and 'Get the f**k out of this neighborhood.'

Video shared online showed thousands of Minneapolis residents taking to the streets following the shooting death of Renee Nicole Good.